A wild weekend in Northern California is capped off with the baseball team’s down 0-2 and the 49ers had a big win.

Today on “Leading Off:”

1. The 49ers cruised to a 45-3 victory over the Bills. Are they back atop The Jason Ross Show power rankings?

2. Do you have a problem with Al Alburqueque kissing the ball then tossing it to first baseman Prince Fielder?

3. The Giants got clobbered last night and now head to Cincinnati down 0-2. Do they have any chance to come back?

4. Who had the best week 5? Who had the worst week 5?