SEATTLE (AP/CBS13) —  Russell Wilson threw four more touchdown passes, two to DK Metcalf, and the Seattle Seahawks rebounded from their first loss of the season with a resounding 37-27 win over the San Francisco 49ers on Sunday.

Wilson and Metcalf tormented San Francisco and its banged-up secondary as the top-scoring offense in the league continued to pile up points. The Seahawks (6-1) have scored at least 30 points in six of seven games.

And for the first time this season at home, the outcome was decided long before the final moments. Seattle opened the year with three home wins over New England, Dallas and Minnesota all of which decided in the final moments.

Thumping their division rivals must have felt downright relaxing, even with the Seahawks having five starters inactive for the game.

“I think it says a tremendous amount that it didn’t matter who was playing,” Seattle coach Pete Carroll. “The guys just stepped up and did their job and busted your tails to get it done.”

Wilson hit Metcalf on a pair of first-half touchdown passes, but it was a 2½-minute sequence midway through the third quarter when Seattle blew the game open.

Wilson found rookie DeeJay Dallas on a 2-yard TD pass after San Francisco went three-and-out to open the second half for a 20-7 lead. Dante Pettis fumbled the ensuing kickoff on a big hit from Cody Barton. Six plays later, Wilson evaded pressure in the pocket and zipped a 6-yard TD pas to David Moore for a 27-7 lead.

Seattle added one more score on a 1-yard TD run by Dallas with 3:33 left after the 49ers pulled within 10.

Wilson finished 27 of 37 for 261 yards and has 26 TD passes on the season, one behind Tom Brady for the most in the first seven games of a season.

Metcalf had another career day in his breakout second season. Metcalf had 102 yards receiving in the first half and finished with a career-high 12 catches and 161 yards receiving.

“I don’t think there is anybody better in terms of what he can do and how he’s done it,” Wilson said. “And he’s only in his second year.”

The momentum from two straight wins for San Francisco (4-4) evaporated in a hurry as more injuries continued to pile. Jimmy Garoppolo was just 11 of 16 for 84 yards and an ugly interception in the first quarter. Garoppolo went to the locker room early in the fourth quarter with an ankle injury and was replaced by Nick Mullens.

Running back Tevin Coleman returned for the first time since early in the season, only to leave at halftime with a knee injury. George Kittle made a terrific 25-yard catch early in the fourth quarter, but limped to the locker room with a foot injury.

“It still hurts each time,” 49ers fullback Kyle Juszczyk said. “Even though it seems to happen over and over again, guys dropping every game, it still hurts every time.”

Mullens led San Francisco on three TD drives in the fourth quarter. He capped the second with a 16-yard TD pass to Ross Dwelley with 4:16 left, but the 2-point conversion failed after replay ruled Jerick McKinnon was touched down short of the goal line.

Mullens was 18 of 25 for 238 yards and two touchdowns. Seattle’s league-worst defense had shut down the 49ers for three quarters before giving up 20 fourth-quarter points.

“I was frustrated with the whole offense, starting with myself. This wasn’t a very good day for us,” 49ers coach Kyle Shanahan said.

INJURIES

The Seahawks played without five starters and one key backup. Chris Carson, Carlos Hyde, Jamal Adams, Benson Mayowa, Ugo Amadi and Mike Iuptai were all inactive due to injuries.

San Francisco played without starters Deebo Samuel, Jeff Wilson Jr., Kwon Alexander and safety Jaquiski Tartt.

UP NEXT

49ers: have a quick turnaround and will host Green Bay on Thursday night.

Seahawks: travel to Buffalo and a showdown with the Bills next Sunday.

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